Trial with Platelet-Rich Fibrin and Bio-Oss used as grafting materials in the treatment of the severe maxillar bone atrophy: clinical and radiological evaluations

F. Inchingolo*•, M. Tatullo#, M. Marrelli*•, A.M. Inchingolo•^, S. Scacco#, A.D. Inchingolo•*, G. Dipalma*•, D. Vermesan°, A. Abbinante, R. Cagiano

School in “Dental Hygiene”, Faculty of Medicine, University “Aldo Moro”, Bari (Italy) *Department of Dental Sciences and Surgery, Faculty of Medicine, University of Bari (Italy) ^Dental School, Faculty of Medicine, University of Milano, Milano (Italy) #Department of Medical Biochemistry and Medical Biology, Faculty of Medicine, University of Bari (Italy) °University of Medicine and Pharmacy “Victor Babes”, Timisoara (Romania) •Calabro-Dental s.r.l. Maxillo-Facial Surgery, Crotone (Italy)

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• Odontostomatology

Abstract. – Objectives: The aim of the present study is to assess the implant osteo-integration, as well as the course of bone regeneration and healing processes, thanks to the sinus lift procedure and by using PRF® as a filling material, in association with the Bio-Oss®.
Materials and Methods: 23 patients, requiring maxillary sinus lift in order to place implants into posterior maxillary region, were involved in this study. Selected cases, in which the height of the residual bone was superior to 5 mm, were adopted for surgical procedure of “one-stage sinus lift” (implant insertion concurrently occured with sinus lift resulting 6-9 months the healing and integration time). Before inserting the implant, a small quantity of filling material was placed in the cavity. For this purpose the bone fragment, stored in saline solution, was employed mixed with Bio-Oss® and PRF®, after being ground.
Results: All patients reported no pain to percussion, no sign of tissue suffering in the soft peri-implant tissues, the presence of an optimal primary stability of the inserted implants and a significant increase in the peri-implant bone density.
Conclusions: In all cases included in this protocol, the Authors observed a successful implant-prosthetic rehabilitation, according with Albrektsson criteria.

Corresponding Author: Raffaele Cagiano, MD; e-mail: r.cagiano@farmacol.uniba.it